UPDATE ON MULTIDRUG-RESISTANT TUBERCULOSIS: CHALLENGES AND OPPORTUNITIES IN THE TREATMENT OF ADULT PATIENTS WORLDWIDE COMPARED TO PANAMA FROM 2004 –2023

Authors

  • Stav Birger Latina University of Panama, student of the Doctor of Medicine and Surgery program. Panama, Panama City.
  • Sapir Leibovitch Latina University of Panama, student of the Doctor of Medicine and Surgery program. Panama, Panama City.
  • Ana Sofia Moreno Latina University of Panama, student of the Doctor of Medicine and Surgery program. Panama, Panama City.
  • Hannah Olle Latina University of Panama, student of the Doctor of Medicine and Surgery program. Panama, Panama City.
  • Ana Laura Parra Latina University of Panama, student of the Doctor of Medicine and Surgery program. Panama, Panama City.
  • Anlly Añez Latina University of Panama, student of the Doctor of Medicine and Surgery program. Panama, Panama City.

Keywords:

Multidrug resistant tuberculosis (MDR-TB), Panama, Treatment strategies, comorbidities

Abstract

Multidrug-resistant tuberculosis (MDR-TB) presents global challenges. In this study, we compare the treatment of MDR-TB in adults worldwide and in Panama. Resistance can be primary (without previous treatment) or secondary (due to failed treatments). Global incidence is influenced by environmental factors, living conditions, lifestyle, medical history, and comorbidities such as diabetes and HIV. The treatment of MDR-TB aims to limit disease progression and transmission, emphasizing the importance of adherence. In Panama, the Ministry of Health (MINSA) employs standardized chemotherapy regimens but faces administrative challenges in reporting cases, affecting treatment coverage. Treatment costs are high, and quality-assured medications are expensive, posing a risk for resource-limited countries. Novel diagnostic and therapeutic approaches, such as the FAST protocol and other treatments, show promise in improving outcomes. Surgical resection can complement medical treatment in cases of multiple drug resistance. However, the adverse effects of medications and the need for prolonged treatment remain concerns, requiring comprehensive health system involvement in combating this international epidemiological problem.

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Published

2024-07-29

How to Cite

Birger, S., Leibovitch, S., Moreno, A. S., Olle, H., Parra, A. L., & Añez, A. (2024). UPDATE ON MULTIDRUG-RESISTANT TUBERCULOSIS: CHALLENGES AND OPPORTUNITIES IN THE TREATMENT OF ADULT PATIENTS WORLDWIDE COMPARED TO PANAMA FROM 2004 –2023. Scientific Behavior, 7(2), 9–33. Retrieved from https://revistas.ulatina.edu.pa/index.php/conductacientifica/article/view/367

Issue

Vol. 7 No. 2 (2024): Scientific Conduct, Journal of Health Sciences Research

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Articles

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Copyright (c) 2024 Stav Birger, Sapir Leibovitch, Ana Sofia Moreno, Hannah Olle, Ana Laura Parra, Anlly Añez

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